Search results for abx000161

Retinoblastoma Protein 1 Phospho-Ser811 (RB1 pS811) Antibody, Abbexa, abx000161

RB1 (pS811) Antibody is a Rabbit Polyclonal antibody against RB1 (pS811). The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB1), bladder cancer, and osteogenic sarcoma.