Search results for abx000189

Signal Transducer and Activator of Transcription 4 Phospho-Tyr693 (STAT4 pY693) Antibody, Abbexa, abx000189

STAT4 (pY693) Antibody is a Rabbit Polyclonal antibody against STAT4 (pY693). The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.