Search results for abx000786

T-Cell Leukemia/lymphoma Protein 1A (TCL1A) Antibody, Abbexa, abx000786

TCL1A Antibody is a Rabbit Polyclonal antibody against TCL1A. Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements. In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730).