Search results for abx001148

Tumor Necrosis Factor Receptor Superfamily Member 10B / DR5 (TNFRSF10B) Antibody, Abbexa, abx001148

TNFRSF10B Antibody is a Rabbit Polyclonal antibody against TNFRSF10B. The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.