Search results for abx001202

Osteopontin (SPP1) Antibody, Abbexa, abx001202

SPP1 Antibody is a Rabbit Polyclonal antibody against SPP1. Osteopontin (SPP1), also designated bone sialoprotein 1, urinary stone protein, spp-1, Eta-1, nephropontin and uropontin, is an extracellular matrix cell adhesion phosphoglycoprotein. SPP1 is deposited into unmineralized matrix prior to calcification leading to localization at various tissue interfaces including cement lines, lamina limitans and between collagen fibrils of fully matured hard tissues. While SPP1 is a major product of osteoblasts, it is also synthesized by brain and kidney cells. SPP1 isolated from or secreted by various tissues ranges in molecular weight due to posttranslational modifications. SPP1 functions as a substrate for transglutaminase and is involved in cell adhesion, chemoattraction and immunomodulation.