Search results for abx001571

Pyruvate Kinase, Liver And RBC (PKLR) Antibody, Abbexa, abx001571

PKLR Antibody is a Rabbit Polyclonal antibody against PKLR. The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.