Search results for abx001575

Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 (BUB1) Antibody, Abbexa, abx001575

BUB1 Antibody is a Rabbit Polyclonal antibody against BUB1. This gene encodes a Serine/Threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.