Search results for abx001900

Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1) Antibody, Abbexa, abx001900

UHRF1 Antibody is a Rabbit Polyclonal antibody against UHRF1. UHRF1, also named as ICBP90, NP95 and RNF106, is a putative E3 ubiquitin-protein ligase. It may participate in methylation-dependent transcriptional regulation. UHRF1 binds to inverted 5'-CCAAT-3' box 2 in the TOP2A promoter, and activates TOP2A expression. It is important for G1/S transition and may be involved in DNA repair and chromosomal stability. UHRF1's ability to repress its direct target gene expression is dependent on PHD(UHRF1) binding to unmodified H3R2.