Search results for abx002045

Amyloid Beta Precursor Like Protein 1 (APLP1) Antibody, Abbexa, abx002045

APLP1 Antibody is a Rabbit Polyclonal antibody against APLP1. This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.