Search results for abx002630

Tumor Necrosis Factor Receptor Superfamily Member 4 / CD134 (TNFRSF4) Antibody, Abbexa, abx002630

TNFRSF4 Antibody is a Rabbit Polyclonal antibody against TNFRSF4. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.