Search results for abx004746

Serpin Family E Member 1 (SERPINE1) Antibody, Abbexa, abx004746

SERPINE1 Antibody is a Rabbit Polyclonal antibody against SERPINE1. This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.