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Caspase Recruitment Domain Family Member 11 (CARD11) Antibody Brand Logo
ID: BAB707253903

Caspase Recruitment Domain Family Member 11 (CARD11) Antibody, Abbexa, abx005391

CARD11 Antibody is a Rabbit Polyclonal antibody against CARD11. The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.

Host

Rabbit

Reactivity

Human, Mouse, Rat

Applications

ELISA, WB, IF/ICC

Conjugation

Unconjugated

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