Search results for abx005510

Runt Related Transcription Factor 3 (RUNX3) Antibody, Abbexa, abx005510

RUNX3 Antibody is a Rabbit Polyclonal antibody against RUNX3. This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.