Search results for abx011003

Interleukin 16 (IL16) Antibody, Abbexa, abx011003

Interleukin-16, also known as lymphocyte chemoattractant factor (LCF), is a chemotactic cytokine that stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils through binding to the CD4 receptor. IL-16 induces human T-lymphocyte expression of interleukin 2 receptor and upregurates major histocompatibility complex II molecules on resting human T lymphocyte. It is able to render CD4+ T cells unresponsive to TCR/CD3 stimuli. Moreover, IL-16 inhibits the replication of T cell and monocyte tropic HIV strains in vitro.