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Matrix Metalloproteinase-9 (MMP9) Antibody Brand Logo
ID: BAB091047065

Matrix Metalloproteinase-9 (MMP9) Antibody, Abbexa, abx011175

MMP9 antibody detects endogenous levels of total MMP9. MMP9 May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. Belongs to the peptidase M10A family. Activated by 4-aminophenylmercuric acetate and phorbol ester. Exists as monomer or homodimer; disulfide-linked. Exists also as heterodimer with a 25 kDa protein. Macrophages and transformed cell lines produce only the monomeric form. Interacts with ECM1.

Host

Rabbit

Reactivity

Human

Applications

WB, IHC

Conjugation

Unconjugated

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