Search results for abx011687

Beta-Adrenergic Receptor Kinase 1 (GRK2) Antibody, Abbexa, abx011687

The product of this gene phosphorylates the beta 2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. (provided by RefSeq)Tissue specificity: Expressed in peripheral blood leukocytes.