Search results for abx012055

Kelch Like ECH Associated Protein 1 (KEAP1) Antibody, Abbexa, abx012055

This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.