Search results for abx015714

High Affinity Nerve Growth Factor Receptor (NTRK1) Antibody, Abbexa, abx015714

TrkA, also known as NTRK1, MTC, TRK, TRK1.It is a member of the neurotrophic tyrosine kinase receptor (NTKR) family.This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway.The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes.Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.