Search results for abx015740

EPH Receptor A4 (EphB4) Antibody, Abbexa, abx015740

EphB4: EPH receptor B4.Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system.Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins.The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.