Search results for abx015891

Interleukin 2 Receptor Alpha (IL2RA) Antibody, Abbexa, abx015891

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor.Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor.Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis.Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown.Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.; ; ; ;.