Search results for abx015925

Protein Mdm4 (MDM4) Antibody, Abbexa, abx015925

MDM4, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal.The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein.The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested.MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein.MDM4 shows significant structural similarity to p53-binding protein MDM2.