Search results for abx015952

Paired Box 3 (PAX3) Antibody, Abbexa, abx015952

This gene is a member of the paired box (PAX) family of transcription factors.Members of the PAX family typically contain a paired box domain and a paired-type homeodomain.These genes play critical roles during fetal development.Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma.The translocation t (2;13) (q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma.Alternative splicing results in transcripts encoding isoforms with different C-termini.