Search results for abx016036

Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Antibody, Abbexa, abx016036

MAP4K4: mitogen-activated protein kinase kinase kinase kinase 4.The protein encoded by this gene is a member of the serine/threonine protein kinase family.This kinase has been shown to specifically activate MAPK8/JNK.The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway.Alternatively spliced transcript variants encoding different isoforms have been identified.