Search results for abx016044

POU Class 5 Homeobox 1 / OCT4 (POU5F1) Antibody, Abbexa, abx016044

Members of Oct family of transcription factors specifically interact with Octamer motif ATGCAAAT, a regulatory element important for tissue- and cell-specific transcription as well as for transcription of a number of housekeeping genes.All of the members of the Oct family contain two highly conserved domains which are separated by 14-26 variable amino acids.These include the POU homeodomain and the POU-specific domain.Both are required for DNA binding and are involved in protein-protein interactions.Evidences indicate that regulation of Oct family transcription factors occurs at the level of phosphorylation.Oct4 is renowned as a transcription factor expressed by undifferentiated embryonic stem cells and embryonic germ cells.