Search results for abx016060

Mouse TUG Antibody, Abbexa, abx016060

The TUG protein contains a UBX domain, for GLUT4.In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes.Full-length TUG forms a complex specifically with GLUT4.In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin.Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.