Search results for abx016082

KSHV ORF8 Antibody, Abbexa, abx016082

Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma- (2)-herpesvirus subfamily and has been closely linked to the Kaposi’s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman’s disease.The genome of KSHV is 165-170 kb and contains at least 88 open reading frames.KSHV ORF8 is a virion envelope-associated protein.Akula et al (2003) report it acts as a Glycoprotein B mediated signaling during virus entry.This Glycoprotein possesses the Arg-Gly-Asp (RGD) motif and utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells.