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Procalcitonin / PCT (CALCA) Antibody (Detection Ab) (Biotin) Brand Logo
ID: BAB381020455

Procalcitonin / PCT (CALCA) Antibody (Detection Ab) (Biotin), Abbexa, abx019264

Procalcitonin (PCT) is a peptide precursor of the hormone calcitonin, the latter being involved with calcium homeostasis. It is composed of 116 amino acids and is produced by parafollicular cells (C cells) of the thyroid and by the neuroendocrine cells of the lung and the intestine. Measurement of procalcitonin can be used as a marker of severe sepsis caused by bacteria and generally grades well with the degree of sepsis, although levels of procalcitonin in the blood are very low. PCT has the greatest sensitivity (85%) and specificity (91%) for differentiating patients with systemic inflammatory response syndrome (SIRS) from those with sepsis, when compared with IL-2, IL-6, IL-8, CRP and TNF-alpha. It is a biomarker of bacterial infection which may help gauge the severity and prognosis of patients with CAP. In addition to clinical predictors, PCT may assist in decisions pertaining to timing of discharge from hospital and the discontinuation of antibiotics. PCT (Detection Antibody) (Biotin) is a Mouse Monoclonal antibody conjugated to Biotin against Human PCT. It is recommended to use abx019247 as the capture antibody and abx019248 or abx019264 (this product) as the detection antibody.

Host

Mouse

Reactivity

Human

Applications

ELISA, WB, CLIA, TIA

Conjugation

Biotin

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