Search results for abx027153

Bak (BH3 Domain Specific) Antibody, Abbexa, abx027153

BAK belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BAK localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.