Search results for abx027344

Rho Guanine Nucleotide Exchange Factor 26 / SGEF (ARHGEF26) Antibody, Abbexa, abx027344

SGEF/ARHGEF26 activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.