Search results for abx027350

Membrane Associated Ring-CH-Type Finger 4 (MARCHF4) Antibody, Abbexa, abx027350

Membrane Associated Ring-CH-Type Finger 4 (MARCHF4) is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCHF4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]).