Search results for abx028049

Histamine N-Methyltransferase (HNMT) Antibody, Abbexa, abx028049

In mammals, histamine is metabolized by two major pathways: N (tau) methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. HNMT is the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N (tau) methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells.