Search results for abx031758

Signaling Lymphocytic Activation Molecule Family Member 1 / CD150 (SLAMF1) Antibody, Abbexa, abx031758

SLAMF1 is high-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11) dependent signal transduction operates.