Search results for abx032087

Caspase 3 Cleaved-Asp175 (CASP3 Cleaved-D175) Antibody, Abbexa, abx032087

Caspase 3 Cleaved-Asp175 (CASP3 Cleaved-D175) antibody is a Rabbit polyclonal against Caspase 3 (cleaved at Asp175). CASP3 encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.