Search results for abx034495

Transmembrane Protein 173 (TM173) Antibody, Abbexa, abx034495
Acts as a facilitator of innate immune signaling. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, FCM
Conjugation
Unconjugated
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