Search results for abx034837
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ID: BAB530283947
NF-Kappa-B Inhibitor Alpha (NFKBIA) Antibody, Abbexa, abx034837
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
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