Search results for abx117221

Protein Wnt-5a (WNT5A) Antibody, Abbexa, abx117221

WNT5A Antibody is a Rabbit Polyclonal antibody against WNT5A. The Wnt family includes several secreted glycoproteins that play important roles in animal developmentThere are 19 Wnt genes in the human genome that encode functionally distinct Wnt proteinsWnt members bind to the Frizzled family of seven-pass transmembrane proteins and activate several signaling pathwaysThe canonical Wnt/β-catenin pathway also requires a coreceptor from the low-density lipoprotein receptor familyAberrant activation of Wnt signaling pathways is involved in several types of cancersWnt-5a has been shown to signal through the canonical Wnt pathways as well as through non-canonical pathways and is up-regulated in various types of human cancersIn melanoma, WNT5A is thought to directly affect cell motility and metastasis.