Search results for abx147721

Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) Antibody, Abbexa, abx147721

Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) Antibody is a Rabbit Polyclonal antibody for the detection of AKR1C2. This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.