Search results for abx148921

Caspase 1 (CASP1) Antibody, Abbexa, abx148921

Caspase 1 (CASP1) Antibody is a Rabbit Polyclonal antibody for the detection of Caspase 1. CASP1 (caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta (IL1B), IL18, and IL33 precursor proteins. The active caspase-1 can increase cellular membrane permeability and intracellular calcium levels, which facilitates lysosome exocytosis and release of host antimicrobial factors and microbial products (PMID:21804020). It has 5 isoforms produced by alternative splicing.