Search results for abx236064

Cyclin-Dependent Kinase Inhibitor 2A / P16-INK4A Antibody, Abbexa, abx236064

CDKN2A / P16-INK4A Antibody is a Rabbit Polyclonal against CDKN2A. CDKN2A generates several transcript variants which differ in their first exons. At least three alternatively-spliced variants encoding distinct proteins have been reported, and two are related, named p16-INK4 and p14 respetively, sharing 50% identity. The third one is completely stuctually un-related, called p14(ARF) or p19(ARF). This antibody reacts with p16 specifically. P16 plays an important role in regulating the cell cycle, and mutations in p16 increase the risk of developing a variety of cancers, notably melanoma.