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Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2) Antibody Brand Logo
ID: BAB294571855

Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2) Antibody, Abbexa, abx240128

Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2) Antibody is a Rabbit Polyclonal antibody for the detection of Autotaxin. Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor.

Host

Rabbit

Reactivity

Human, Mouse, Rat

Applications

ELISA, WB, IHC

Conjugation

Unconjugated

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