Search results for abx240299

Stimulator of Interferon Genes Protein / TMEM173 (STING1) Antibody, Abbexa, abx240299

Stimulator of Interferon Genes Protein / TMEM173 (STING1) Antibody is a Mouse Monoclonal antibody for the detection of STING1. This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.