Search results for abx365176

Immunoglobulin G-Binding Protein A (spa) ELISA Kit, Abbexa, abx365176

Immunoglobulin G-Binding Protein A (spa) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Immunoglobulin G-Binding Protein A (Staphylococcus aureus Protein A) concentrations in serum, plasma and other biological fluids. Protein G can be used as an affinity ligand in protein and antibody purification processes. This kit is designed to detect residual protein G concentrations remaining after the purification of recombinant proteins and antibodies. Protein A also known as staphylococcus aureus protein A (spa) is a 40-60 kDa surface protein found in the cell wall of Staphylococcus aureus. The carboxyl terminal end of Protein A is anchored to the staphylococcus cell wall by the transpeptidase enzyme sortase. It is encoded by the spa gene and consists of five homologous 6.7 kDA immunoglobulin domains (E, D, A, B, and C) joined by conserved linkers of six to nine residues. Protein A has been shown to stimulate inflammatory responses by interacting with several proteins including tumor necrosis factor alpha receptors, Willebrand factor and C1qR, and also has an important role in diagnostics due to it's ability to bind to the Fab and Fc fragments of a wide range of mammalian immunoglobulins.