Search results for abx382513

Human Proteasome Subunit Beta Type-3 (PSMB3) ELISA Kit, Abbexa, abx382513

Human Proteasome Subunit Beta Type-3 (PSMB3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Proteasome Subunit Beta Type-3 (PSMB3) concentrations in tissue homogenates, cell lysates and other biological fluids. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. The 26 S proteasome may be involved in trinucleotide repeat expansion, a phenomenon which is associated with many hereditary neurological diseases. Pseudogenes have been identified on chromosomes 2 and 12.