Search results for abx382515

Human Proteasome Subunit Beta Type 5 (PSMB5) ELISA Kit, Abbexa, abx382515

Human Proteasome Subunit Beta Type 5 (PSMB5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Proteasome Subunit Beta Type 5 (PSMB5) concentrations in tissue homogenates, cell lysates and other biological fluids. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Multiple transcript variants encoding different isoforms have been found for this gene.