Search results for abx831003

Apolizumab, Abbexa, abx831003

Apolizumab is a monoclonal antibody biosimilar expressed in CHO cells, targeting HLA-DRB, for use in laboratory research applications. This product is not suitable for use as medicines or in human, therapeutic or diagnostic applications. Apolizumab is a humanized monoclonal antibody that is being studied as a treatment for hematologic cancers. Apolizumab is a humanized monoclonal antibody directed against 1D10, a polymorphic determinant on the HLA-DR beta chain that is expressed on normal and neoplastic B cells. Apolizumab induces complement-mediated cytotoxicity, antibody-dependent cell-mediated cytotoxicity, and apoptosis of 1D10 antigen-positive B cells in vitro.