Search results for abx831049

Muromonab, Abbexa, abx831049

Muromonab is a monoclonal antibody biosimilar expressed in CHO cells, targeting CD3E, for use in laboratory research applications. This product is not suitable for use as medicines or in human, therapeutic or diagnostic applications. Murine monoclonal antibody specific to CD3 T-cell lymphocyte antigens. More specifically it is a purified murine (mouse) monoclonal antibody, directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes) cultured using the murine ascites method. Muromonab is 93% monomeric immune globulin G type 2a (IgG2a). Muromonab binds to the T-cell surface glycoprotein CD3 epsilon chain. It appears to kill CD-3 positive cells by inducing Fc mediated apoptosis, antibody mediated cytotoxicity and complement-dependent cytotoxicity.