Search results for cell division cycle 20
Cell Division Cycle 20 (CDC20) Antibody, Abbexa, abx001143
CDC20 Antibody is a Rabbit Polyclonal antibody against CDC20. CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation.
Host
Rabbit
Reactivity
Human
Applications
WB
Conjugation
Unconjugated
Cell Division Cycle 20 (CDC20) Antibody, Abbexa, abx034241
CDC20 is an activating regulatory factor for the APC/C (anaphase promoting complex/cyclosome). It activates the ubiquitination activity of the APC/C. CDC20 confers a strict destruction-box (D-box) dependence on APC. Levels of CDC20, as well as its binding to APC, peak in mitosis and decrease drastically at early G1.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, FCM
Conjugation
Unconjugated
Cell Division Cycle 20 (Cdc20) Antibody, Abbexa, abx231518
Cdc20 Antibody is a Rabbit Polyclonal against Cdc20.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IP
Conjugation
Unconjugated
Cell Division Cycle 20 (CDC20) Antibody, Abbexa, abx148978
Cell Division Cycle 20 (CDC20) Antibody is a Rabbit Polyclonal antibody for the detection of Cdc20. Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Rat Cell Division Cycle 20 (CDC20) ELISA Kit, Abbexa, abx505839
Rat Cell Division Cycle 20 (CDC20) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Cell division cycle protein 20 homolog concentrations in tissue homogenates, cell lysates and other biological fluids.
Host
Reactivity
Rat
Applications
ELISA
Conjugation
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1) Antibody, Abbexa, abx112545
Fizzy/Cell Division Cycle 20 Related 1 (Drosophila) Antibody is a Rabbit Polyclonal antibody against Fizzy/Cell Division Cycle 20 Related 1 (Drosophila).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1) Antibody, Abbexa, abx233265
FZR1 Antibody is a Rabbit Polyclonal against FZR1.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1) Antibody, Abbexa, abx004249
FZR1 Antibody is a Rabbit Polyclonal antibody against FZR1.
Host
Rabbit
Reactivity
Human, Mouse
Applications
IF/ICC
Conjugation
Unconjugated
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1) Antibody, Abbexa, abx302880
FZR1 Antibody is a Rabbit Polyclonal against FZR1.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1) Antibody, Abbexa, abx030710
Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C), which confers substrate specificity upon the complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. Following DNA damage, it is required for the G2 DNA damage checkpoint: its dephosphorylation and reassociation with the APC/C leads to the ubiquitination of PLK1, preventing entry into mitosis.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
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