Search results for member 1 (glucocorticoid receptor)
Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) Antibody, Abbexa, abx117236
NR3C1 Antibody is a Rabbit Polyclonal antibody against NR3C1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) Antibody, Abbexa, abx011844
The protein encoded by this gene is a receptor for glucocorticoids and can act as both a transcription factor and a regulator of other transcription factors. The encoded protein can bind DNA as a homodimer or as a heterodimer with another protein such as the retinoid X receptor. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC, FCM
Conjugation
Unconjugated
Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) Antibody, Abbexa, abx031242
The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) Antibody, Abbexa, abx034782
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation (By similarity).
Host
Mouse
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) Antibody, Abbexa, abx001776
NR3C1 Antibody is a Rabbit Polyclonal antibody against NR3C1. This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
Conjugation
Unconjugated
Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) Antibody, Abbexa, abx037382
Rabbit Polyclonal against the NR3C1 protein.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
.png "Click to View Glucocorticoid Receptor (D6H2L) Rabbit Monoclonal Antibody (Biotinylated)#58122 Product Detail")
Glucocorticoid Receptor (D6H2L) Rabbit Monoclonal Antibody (Biotinylated)#58122, Cell Signaling Technology (CST), 58122
Glucocorticoid Receptor (D6H2L) Rabbit Monoclonal Antibody (Biotinylated) recognizes endogenous levels of total GR protein. This antibody reacts with GR-α and GR-β but does not cross-react with mineralocorticoid receptor.
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Applications
Western Blotting: 1:1000
Conjugation
Glucocorticoid Receptor (D8H2) Rabbit Monoclonal Antibody (Alexa Fluor®488 Conjugate)#12007, Cell Signaling Technology (CST), 12007
Glucocorticoid Receptor (D8H2) Rabbit Monoclonal Antibody (Alexa Fluor®488 Conjugate) recognizes endogenous levels of total glucocorticoid receptor protein. Based upon sequence alignment, this antibody conjugate is predicted to cross-react with all known alternative translation start site generated isoforms of glucocorticoid receptor-α and glucocorticoid receptor-β. This antibody conjugate does not cross-react with mineralocorticoid receptor.
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Applications
Immunofluorescence (Immunocytochemistry): 1:400 - 1:800 Flow Cytometry (Fixed/Permeabilized): 1:50
Conjugation
Glucocorticoid Receptor (D8H2) Rabbit Monoclonal Antibody (Alexa Fluor®647 Conjugate)#55716, Cell Signaling Technology (CST), 55716
Glucocorticoid Receptor (D8H2) Rabbit Monoclonal Antibody (Alexa Fluor®647 Conjugate) recognizes endogenous levels of total glucocorticoid receptor protein. Based upon sequence alignment, this antibody conjugate is predicted to cross-react with all known alternative translation start site generated isoforms of glucocorticoid receptor-α and glucocorticoid receptor-β. This antibody conjugate does not cross-react with mineralocorticoid receptor.
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Applications
Flow Cytometry (Fixed/Permeabilized): 1:50
Conjugation
Glucocorticoid Receptor (D8H2) Rabbit Monoclonal Antibody (PE Conjugate)#19560, Cell Signaling Technology (CST), 19560
Glucocorticoid Receptor (D8H2) Rabbit Monoclonal Antibody (PE Conjugate) recognizes endogenous levels of total glucocorticoid receptor protein. Based upon sequence alignment, this antibody conjugate is predicted to cross-react with all known alternative translation start site generated isoforms of glucocorticoid receptor-α and glucocorticoid receptor-β. This antibody conjugate does not cross-react with mineralocorticoid receptor.
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Applications
Flow Cytometry (Fixed/Permeabilized): 1:50
Conjugation
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