Search results for palmitoyl-protein thioesterase 1
Palmitoyl-Protein Thioesterase 1 Antibody, Abbexa, abx114319
Palmitoyl-Protein Thioesterase 1 Antibody is a Rabbit Polyclonal antibody against Palmitoyl-Protein Thioesterase 1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Palmitoyl-Protein Thioesterase 1 (PPT1) Antibody, Abbexa, abx031626
Palmitoyl-protein thioesterase-1 (PPT1) is a lysosomal hydrolase that removes long-chain fatty acyl groups from modified cysteine residues in proteins. Mutations in PPT1 have been found to cause the infantile form of neuronal ceroid lipofuscinosis (INCL), and an animal model has been developed.1 The deduced PPT2 protein contains 302 amino acids, including a 27-amino acid leader peptide, a sequence motif characteristic of many thioesterases and lipases, and 5 potential N-linked glycosylation sites.2 PPT2 shares 18% amino acid identity with PPT1. Northern blot analysis detected a predominant 2.0-kb PPT2 transcript in the human tissues examined, with the highest expression in skeletal muscle; variable amounts of 2.8 and 7.0-kb transcripts were also observed. Recombinant PPT2, like PPT1, possesses thioesterase activity and localizes to the lysosome. Since PPT2 could not substitute for PPT1 in correcting the metabolic defect in INCL cells and was unable to remove palmitate groups from palmitoylated proteins that are routinely used as substrates for PPT1it has been postulated that PPT2 possesses a different substrate specificity than PPT1.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Palmitoyl Protein Thioesterase 1 (PPT1) Antibody, Abbexa, abx129705
Palmitoyl Protein Thioesterase 1 Antibody is a Rabbit Polyclonal against Palmitoyl Protein Thioesterase 1.
Host
Rabbit
Reactivity
Mouse
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Palmitoyl-Protein Thioesterase 1 (PPT1) Antibody, Abbexa, abx122623
Rabbit Polyclonal against the PPT1 protein.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Palmitoyl-Protein Thioesterase 1 (PPT1) Antibody, Abbexa, abx036288
Rabbit Polyclonal against the PPT1 protein.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Palmitoyl-Protein Thioesterase 1 (PPT1) Antibody, Abbexa, abx236739
PPT1 Antibody is a Rabbit Polyclonal against PPT1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Palmitoyl-Protein Thioesterase 1 (PPT1) Antibody, Abbexa, abx318847
PPT1 Antibody is a Rabbit Polyclonal against PPT1.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Palmitoyl-Protein Thioesterase 1 (PPT1) Antibody, Abbexa, abx031627
Palmitoyl-protein thioesterase-1 (PPT1) is a lysosomal hydrolase that removes long-chain fatty acyl groups from modified cysteine residues in proteins. Mutations in PPT1 have been found to cause the infantile form of neuronal ceroid lipofuscinosis (INCL), and an animal model has been developed.1 The deduced PPT2 protein contains 302 amino acids, including a 27-amino acid leader peptide, a sequence motif characteristic of many thioesterases and lipases, and 5 potential N-linked glycosylation sites.2 PPT2 shares 18% amino acid identity with PPT1. Northern blot analysis detected a predominant 2.0-kb PPT2 transcript in the human tissues examined, with the highest expression in skeletal muscle; variable amounts of 2.8 and 7.0-kb transcripts were also observed. Recombinant PPT2, like PPT1, possesses thioesterase activity and localizes to the lysosome. Since PPT2 could not substitute for PPT1 in correcting the metabolic defect in INCL cells and was unable to remove palmitate groups from palmitoylated proteins that are routinely used as substrates for PPT1it has been postulated that PPT2 possesses a different substrate specificity than PPT1.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Palmitoyl Protein Thioesterase 1 (PPT1) Antibody, Abbexa, abx326467
PPT1 Antibody is a Rabbit Polyclonal against PPT1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Palmitoyl-Protein Thioesterase 1 (PPT1) Antibody (Biotin), Abbexa, abx317128
PPT1 Antibody (Biotin) is a Rabbit Polyclonal against PPT1 conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
Please provide the required information below so that we can quickly source your products.