Search results for receptor tyrosine kinase
Related To Receptor Tyrosine Kinase (RYK) Antibody, Abbexa, abx103651
Polyclonal Antibody to Related To Receptor Tyrosine Kinase (RYK).
Host
Rabbit
Reactivity
Mouse
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Related To Receptor Tyrosine Kinase (RYK) Antibody, Abbexa, abx129056
Related To Receptor Tyrosine Kinase Antibody is a Rabbit Polyclonal against Related To Receptor Tyrosine Kinase.
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Neurotrophic Receptor Tyrosine Kinase 1 (NTRK1) Antibody, Abbexa, abx025227
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Host
Mouse
Reactivity
Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Muscle Skeletal Receptor Tyrosine Kinase (MUSK) Antibody, Abbexa, abx033586
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, FCM
Conjugation
Unconjugated
Muscle Skeletal Receptor Tyrosine Kinase (MUSK) Antibody, Abbexa, abx214595
MUSK Antibody is a Rabbit Polyclonal against MUSK.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Muscle Skeletal Receptor Tyrosine Kinase (MUSK) Antibody, Abbexa, abx002025
MUSK Antibody is a Rabbit Polyclonal antibody against MUSK. This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.
Host
Rabbit
Reactivity
Mouse
Applications
WB
Conjugation
Unconjugated
Neurotrophic Receptor Tyrosine Kinase 1 (NTRK1) Antibody, Abbexa, abx323165
NTRK1 Antibody is a Rabbit Polyclonal against NTRK1.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC, IF/ICC
Conjugation
Unconjugated
Neurotrophic Receptor Tyrosine Kinase 1 (NTRK1) Antibody, Abbexa, abx326702
NTRK1 Antibody is a Rabbit Polyclonal against NTRK1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Muscle Skeletal Receptor Tyrosine Kinase (MUSK) Antibody, Abbexa, abx033588
MuSK activates signaling cascades responsible for many aspects of synapse formation, including the organization of the postsynaptic membrane, synapse-specific transcription, and presynaptic differentiation. MuSK also mediates agrin-induced aggregation of acetylcholine receptors at the mature vertebrate neuromuscular junction and also during synapse formation. It has been shown that a majority of AChR Ab-seronegative myasthenia gravis patients possess serum autoantibodies against MuSK.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IF/ICC, FCM
Conjugation
Unconjugated
Neurotrophic Receptor Tyrosine Kinase 2 (NTRK2) Antibody, Abbexa, abx328566
NTRK2 Antibody is a Rabbit Polyclonal against NTRK2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
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